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FLASH GENE
Symbol SH3BGRL contributors: - updated : 08-06-2004
HGNC name SH3 domain binding glutamic acid-rich protein like
HGNC id 10823
Location Xq13.3      Physical location : 80.457.302 - 80.554.042
DNA
TYPE functioning gene
STRUCTURE 96.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned   linked   status provisional
Physical map
MGC23937 Xq13.2 hypothetical protein MGC23937 similar to CG4798 LOC389875 X similar to telomeric repeat binding factor 1 isoform 2; Telomeric repeat binding factor 1; telomeric repeat binding protein 1 ZDHHC15 Xq13.1 zinc finger, DHHC domain containing 15 BRAF2 Xq13.2 similar to v-raf murine sarcoma viral oncogene homolog B1 pseudogene LOC286495 Xq13.2 similar to Tetratricopeptide repeat protein 3 (TPR repeat protein D) HCA3 Xq13.2 hepatocellular carcinoma-associated protein HCA3 MGC874 Xq13.2 hypothetical protein MGC874 LDHBP Xq13.2-q13.3 lactate dehydrogenase B pseudogene KIAA1587 Xq13.2 hepatocellular carcinoma-associated protein HCA1 LOC392499 X similar to hypothetical protein FLJ13611 ATRX Xq13.3 alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) DKFZp564K142 Xq13.3 implantation-associated protein COX7B Xq13.1 cytochrome c oxidase subunit VIIb ATP7A Xq13.3 ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) PGK1 Xq13.3 phosphoglycerate kinase 1 TAF9L Xq13.1-q21.1 TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa CYSLTR1 Xq13-q21 cysteinyl leukotriene receptor 1 ZCCHC5 Xq13.3 zinc finger, CCHC domain containing 5 GPR23 Xq13-q21.1 G protein-coupled receptor 23 P2RY10 Xq21.1 purinergic receptor P2Y, G-protein coupled, 10 FKSG79 Xq13.3 putative purinergic receptor LOC347363 Xq13.3 similar to Chromosome-associated kinesin KIF4A (Chromokinesin) ITM2A Xq13.3-q21.2 integral membrane protein 2A TBX22 Xq21.1 T-box 22 MGC26999 Xq21.1 hypothetical protein MGC26999 LOC347364 Xq21.1 similar to WW domain binding protein 11; Npw38-binding protein NpwBP; SH3 domain-binding protein SNP70 LOC286425 Xq21.1 similar to hexokinase 2; hexokinase-2, muscle FLJ38568 Xq21.1 hypothetical protein FLJ38568 LOC286426 Xq21.1 similar to Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) NSBP1 Xq13.3 nucleosomal binding protein 1 SH3BGRL Xq13.3 SH3 domain binding glutamic acid-rich protein like LOC392500 X similar to ribosomal protein L22 LOC266683 Xq13.3 dendritic cell protein pseudogene POU3F4 Xq21.1 POU domain, class 3, transcription factor 4 LOC158668 Xq21.1 similar to Telomeric repeat binding factor 1 (TTAGGG repeat binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1) CYLC1 Xq21.1 cylicin, basic protein of sperm head cytoskeleton 1 RPS6KA6 Xq21 ribosomal protein S6 kinase, 90kDa, polypeptide 6 FLJ30678 Xq21.1 hypothetical protein FLJ30678 MGC42638 Xq21.1 hypothetical protein MGC42638 UNQ8193 Xq21.1 AAIR8193 LOC340562 Xq21.1-q21.2 hypothetical protein LOC340562 ZNF6 Xq21.1 zinc finger protein 6 (CMPX1) POF1B Xq21.2 premature ovarian failure 1B CHM Xq21.2 choroideremia (Rab escort protein 1) LOC347428 Xq21.2 similar to Stress-induced-phosphoprotein 1 (STI1) (Hsp70/Hsp90-organizing protein) (Transformation-sensitive protein IEF SSP 3521) DACH2 Xq21.3 dachshund homolog 2 (Drosophila) bA345E19.2 Xq21.31 COP9 pseudogene
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a proline-rich region containing the consensus sequence of a SH3 domain
  • and a carboxy-terminal glutamic acid rich region,putatively assuming a coiled-coil structure
  • HOMOLOGY
    intraspecies homolog to SH3BGR
    Homologene
    FAMILY SH3BGR family
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,nucleus
    basic FUNCTION may be functioning as endogenous modulators of GRX activity.
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SH3 domain binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS