basic FUNCTION
| potentially involved in hormone and cytokine cellular pathway |
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required for both male and female reproduction |
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required for nerve growth factor induced neural differentiation |
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signaling molecule involved in GDNF-induced neurite outgrowth |
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signaling adaptor protein that regulates cellular signaling in various physiological processes |
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key enhancer of RET physiologic and pathologic activities |
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SH2 domain-containing adaptor protein, and a new regulator of insulin expression |
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in beta-cells promotes insulin synthesis and secretion at least in part by enhancing activation of JAK2 and/or PDX1 pathways in response to hormonal and nutritional signals |
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can enhance neurite outgrowth and accelerate the maturation of induced neurons (iNs) under defined conditions |