basic FUNCTION
| template activating factor I, beta isoform (DNA replication factor) |
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potent and specific inhibitor of protein phosphatase 2A (PPP2AC) |
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involved in DNA replication, in nuclear organization and biogenesis |
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histone chaperone involved in cell-cycle control and chromatin remodeling |
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regulates the CREBBP-mediated transcription |
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required for transcription of chromatin templates by RNA polymerase Pol II |
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with PARP1, may function by physically removing chromatin-bound DEK |
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negative regulator of neuronal development |
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plays a role in MCPH1-mediated chromosome condensation/decondensation |
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important regulator of chromosome condensation/decondensation and disruption of the MCPH1-SET interaction might be important for the pathogenesis of primary microcephaly |
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potent inhibitor of the protein phosphatase 2A (PP2A) tumor suppressor |