basic FUNCTION
| inhibiting extracellular matrix degradation by PLAU |
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putative upregulated c-Myc target gene |
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playing a key role in control of coagulation and tissue remodeling |
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is an intracellular inhibitor of furin, having an active role in the development of metabolic disorders  |
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antiapoptotic role for SERPINE1 that may contribute to its participation in neutrophil-associated inflammatory responses (  |
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endothelial plasminogen activator inhibitor SERPINE1, controls vascular remodeling, angiogenesis and fibrinolysis |
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playing a role in regulation of angiogenesis  |
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involved in the innate immunity by regulating cell migration and phagocytosis  |
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glia-derived SERPINE1 may regulate microglial migration and phagocytosis in an autocrine or paracrine manner  |
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promotes the proliferation, transforming into myofibroblasts, collagen synthesis, and inhibits apoptosis of pulmonary fibroblasts by activating Ca(2+), ERK and AKT signaling pathway  |