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FLASH GENE
Symbol SERPINA7 contributors: mct/npt - updated : 16-04-2008
HGNC name serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
HGNC id 11583
Corresponding disease
TBG thyroxine-binding globulin deficiency
TBGMR psychomotor retardation with TBG deficiency
Location Xq22.2      Physical location : 105.277.189 - 105.282.718
Synonym name
  • thyroxin-binding globulin
  • T4-binding globulin
    • Synonym symbol(s) TBG
    DNA
    TYPE anonymous DNA segment
    STRUCTURE 3.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked Y status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 1559 46.3 415 - Lacka (2007)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveliver    
    cell lineage
    cell lines
    fluid/secretion plasma
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • serpin family
    • CATEGORY enzyme , regulatory
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • serine protease inhibitor, major thyroid hormone transport protein in serum
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) TBG , TBGMR
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS