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FLASH GENE
Symbol SERPINA6 contributors: - updated : 09-12-2005
HGNC name serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
HGNC id 1540
Corresponding disease
CBG corticosteroid binding globulin deficiency
Location 14q32.1      Physical location : 94.770.585 - 94.789.688
Synonym name
  • corticosteroid binding globulin
  • transcortin
  • Synonym symbol(s) CBG
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 19.00 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    text structure ( 5'intronic promoter) binded to several nuclear matrix attachment region (MAR)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Respiratorylung    
    cell lineage
    cell lines hepatoma cells
    fluid/secretion plasma
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY member of the serpin superfamily
    CATEGORY enzyme , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • corticosteroid binding globulin
  • serine proteinase inhibitor
  • involved in the regulation of gene activity and chromatin structure
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CBG
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS