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FLASH GENE

Symbol

SERPINA10

contributors: mct - updated : 19-05-2006

HGNC name	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
HGNC id	15996

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	14q32.13      Physical location : 94.749.651 - 94.759.596
Genatlas name	protein Z-dependent protease inhibitor precursor
Synonym name	centerin
Synonym symbol(s)	PZI, ZPI, CENTERIN

DNA

TYPE	functioning gene
STRUCTURE	9.00 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive liver       highly Reproductive male system testis

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

serpin family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION

inhibiting factor Xa activity in the presence of protein z, calcium and phospholipid

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to venous thrombosis and thrombophilia

Variant & Polymorphism SNP , other	increasing the risk of venous thrombosis and thrombophilia

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS