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FLASH GENE
Symbol SERHL contributors: np/ - updated : 09-12-2005
HGNC name serine hydrolase-like
HGNC id 14408
Location 22q13.2      Physical location : 42.896.584 - 42.908.565
Synonym name kraken-like
Synonym symbol(s) HS126B42, BK126B4.1, dJ222E13.1, SERHL2, dJ222E13.1
EC.number 3.1.-.-
DNA
TYPE functioning gene
STRUCTURE 11.98 kb
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
TNFRSF13C 22q13.1-q13.31 tumor necrosis factor receptor superfamily, member 13C C22orf18 22q13.2-q13.31 chromosome 22 open reading frame 18 SEPT3 22q13.2 septin 3 MGC26816 22q13.31 hypothetical protein MGC26816 NAGA 22q13.2 N-acetylgalactosaminidase, alpha- LOC150368 22q13.31 hypothetical protein LOC150368 LOC91689 22q13.31 hypothetical gene supported by AL449243 NDUFA6 22q13.2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa LOC246785 22q13.2 PTD004 pseudogene CYP2D8P2 22q11.22-q11.23 cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 CYP2D8P1 22q13.2-q13.31 cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 1 TCF20 22q13.3 transcription factor 20 (AR1) LOC388906 22 hypothetical gene supported by BC039496 LOC150371 22q13.31 hypothetical LOC150371 NFAM1 22q13.31 NFAT activation molecule 1 SERHL 22q13.2-q13.31 serine hydrolase-like CGI-96 22q13.2-q13.31 CGI-96 protein dJ222E13.1 22q13 kraken-like dJ222E13.2 22q13.31 similar to CGI-96 PDIP46 RNU12P 22 RNA, U12 small nuclear pseudogene DIA1 22q13.2 diaphorase (NADH) (cytochrome b-5 reductase) A4GALT 22q13.2 alpha 1,4-galactosyltransferase LOC388907 22 similar to ribosomal protein L5; 60S ribosomal protein L5 LOC391337 22 similar to hypothetical protein ARFGAP3 22q13.2-q13.3 ADP-ribosylation factor GTPase activating protein 3 PACSIN2 22q13.31 protein kinase C and casein kinase substrate in neurons 2
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1400 - - ubiquitous, highly in kidneyŁlow in skeletal muscle, small intestine 2001 11352564
- - 2400 - - ubiquitous, highly in kidneyŁlow in skeletal muscle, small intestine 2001 11352564
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal   Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text muscle
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N myristoylation sites conserved C type 1 peroxisomal targeting signal and a serine lipase active center
  • HOMOLOGY
    Homologene
    FAMILY
  • AB hydrolase superfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    basic FUNCTION
  • playing a role in developmental muscle and in normal peroxisome function and skeltal muscle growth in respone to mechanical stimuli
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS