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FLASH GENE
Symbol SEC61G contributors: SGE - updated : 13-04-2010
HGNC name Sec61 gamma subunit
HGNC id 18277
Location 7p11.2      Physical location : 54.819.940 - 54.826.939
Synonym name
  • protein transport protein Sec61 subunit gamma
  • protein transport protein SEC61 gamma subunit
  • Synonym symbol(s) SSS1
    DNA
    TYPE functioning gene
    STRUCTURE 7.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 480 - 68 - Hartmann (1994)
    4 - 484 - 68 - Hartmann (1994)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver   moderately
    Nervousbrain   moderately
    Reproductivemale systemprostate  moderately
    Respiratorylung   moderately
    Urinarykidney   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , trimer
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae SSS1p
    homolog to E.coli SecEp
    homolog to murine Sec61g (100.00pc)
    homolog to rattus Sec61g (100.00pc)
    Homologene
    FAMILY
  • SECE/SEC61-GAMMA family
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    text tail-anchored membrane protein
    basic FUNCTION
  • involved in protein translocation in the endoplasmic reticulum
  • CELLULAR PROCESS protein, post translation, targeting
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text protein transport
    PATHWAY
    metabolism
    signaling
    a component
  • heterotrimer of three membrane proteins- alpha, beta and gamma forming a transmembrane channel (Sec61 complex) where proteins are translocated across and integrated into the ER membrane
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS