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FLASH GENE
Symbol SEC24B contributors: mct/npt - updated : 17-05-2008
HGNC name SEC24 related gene family, member B (S. cerevisiae)
HGNC id 10704
Location 4q25      Physical location : 110.354.970 - 110.461.614
Synonym name
  • SEC24 (S. cerevisiae) related gene family, member B
  • protein transport protein Sec24B
  • secretory protein 24
  • Synonym symbol(s) SEC24, MGC48822
    DNA
    TYPE functioning gene
    STRUCTURE 106.00 kb     23 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Map cen - D4S2945 - D4S1616 - SEC24B - D4S1611 - D4S1580 - D4S427 - D4S402 - D4S430 - qter
    Authors Gene Map (98)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    24 - 4649 138 1268 - Mancias (2007)
    23 - 4544 - 1233 - Mancias (2007)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Respiratoryrespiratory tracttrachea  highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Connectiveadipose  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae Sec24p
    Homologene
    FAMILY
  • SEC23/SEC24 family
  • SEC24 subfamily
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • involved in vesicle biogenesis from endoplasmic reticulum
  • may be implicated in cargo selection and concentration
  • role in selective export of membrane proteins from the endoplasmic reticulum
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SEC13, SEH1L
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS