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FLASH GENE
Symbol SDF2L1 contributors: npt/ - updated : 03-09-2002
HGNC name stromal cell-derived factor 2-like 1
HGNC id 10676
Location 22q11.21      Physical location : 21.996.541 - 21.998.587
Synonym name
  • dihydropyrimidinase-like 2
  • PWP1-interacting protein 8
  • SDF2-like protein 1
  • Synonym symbol(s) SDFL, AP000553.C22.4
    DNA
    TYPE functioning gene
    STRUCTURE 2.05 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC388860 22 similar to Gamma-glutamyltranspeptidase 1 precursor (Gamma-glutamyltransferase 1) (CD224 antigen) LOC388861 22 similar to E2F transcription factor 6 isoform a LOC388862 22 LOC388862 LOC388863 22 similar to dJ831C21.3 (novel protein similar to DKFZP434P211 protein) LOC388864 22 similar to breakpoint cluster region isoform 1 LOC391303 22 similar to Nucleosome binding protein 1 (Nucleosome binding protein 45) (NBP-45) (GARP45 protein) LOC391304 22 similar to KIAA0649 gene product LOC391305 22 similar to Sushi domain (SCR repeat) containing KIAA1666  KIAA1666 protein HIC2 22q11.21 hypermethylated in cancer 2 LOC220686 22q11.22 hypothetical protein LOC220686 LOC150221 22q11.22 similar to hypothetical protein UBE2L3 22q11.22 ubiquitin-conjugating enzyme E2L 3 LOC150223 22q11.22 hypothetical protein LOC150223 FLJ36046 22q11.22 hypothetical protein FLJ36046 SDF2L1 22q11.22 stromal cell-derived factor 2-like 1 LOC388865 22 similar to RIKEN cDNA 2610318N02 PPIL2 22q11.22 peptidylprolyl isomerase (cyclophilin)-like 2 YPEL1 22q11.2 yippee-like 1 (Drosophila) MAPK1 22q11.2 mitogen-activated protein kinase 1 PPM1F 22q11.22 protein phosphatase 1F (PP2C domain containing) FLJ23185 22q11.22 hypothetical protein FLJ23185 TOP3B 22q11 topoisomerase (DNA) III beta LOC391306 22 similar to Hypothetical protein DJ1198H6.2 IGLVI-70 22q11.2 immunoglobulin lambda variable (I)-70 IGLV4-69 22q11.2 immunoglobulin lambda variable 4-69 IGLVI-68 22q11.2 immunoglobulin lambda variable (I)-68 IGLV10-67 22q11.2 immunoglobulin lambda variable 10-67 IGLVIV-66-1 22q11.2 immunoglobulin lambda variable (IV)-66-1 IGLVV-66 22q11.2 immunoglobulin lambda variable (V)-66 IGLVIV-65 22q11.2 immunoglobulin lambda variable (IV)-65
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 876 21 221 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreas   highly
    Reproductivemale systemtestis  highly
     male systemprostate  highly
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text pancreas
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three MIR domains.
  • HDEL motif (endoplasmic reticulum RE, retention-like motif) at the C terminus
  • HOMOLOGY
    interspecies homolog to murine Sdf2l1
    Homologene
    FAMILY
  • glycosyltransferase family 39
  • CATEGORY structural protein
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION unknown
    CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS