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FLASH GENE

Symbol

SDCCAG3

contributors: mct/npt - updated : 15-02-2010

HGNC name	serologically defined colon cancer antigen 3
HGNC id	10667

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	9q34.3      Physical location : 139.296.374 - 139.305.054
Synonym name	antigen NY-CO-3
Synonym symbol(s)	NY-CO-3

DNA

TYPE	functioning gene
STRUCTURE	8.68 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001039707 10 - 2390 NP_001034796 - 435 - Neznanov (2005) NM_001039708 8 - 2171 NP_001034797 - 362 - Neznanov (2005) NM_006643 9 - 2321 NP_006634 - 412 - Neznanov (2005)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine

cell lineage
cell lines	various cancer
fluid/secretion	serum

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

SDCCAG3 family

CATEGORY

antigen

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION

may be is important for protein trafficking and presentation of TNFR1 on the cell surface and can be viewed as a potential target for modulation of TNF response (Neznanov 2005)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS