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FLASH GENE
Symbol SCIN contributors: npt/ - updated : 13-08-2004
HGNC name scinderin
HGNC id 21695
Location 7p21.3      Physical location : 12.610.202 - 12.693.225
Synonym name adseverin
Synonym symbol(s) KIAA1905
DNA
TYPE functioning gene
STRUCTURE 83.03 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 2586 - 468 - -
16 - 3261 - 715 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinepancreas    
Skin/Tegumentskin    
Urinarykidneytubulecollecting duct  
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveenterocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a gelsolin homology domain
  • three actin-binding sites
  • two phosphatidylinositol bisphosphate-binding sites
  • HOMOLOGY
    interspecies homolog to rattus LOC298975
    Homologene
    FAMILY
  • villin/gelsolin family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION
  • may have a regulatory function in exocytosis, affecting the organisation of the microfilament network
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • actin binding
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS