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FLASH GENE
Symbol SCIN contributors: npt/ - updated : 13-08-2004
HGNC name scinderin
HGNC id 21695
Location 7p21.3      Physical location : 12.610.202 - 12.693.225
Synonym name adseverin
Synonym symbol(s) KIAA1905
DNA
TYPE functioning gene
STRUCTURE 83.03 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
FLJ13576 7q31.32 hypothetical protein FLJ13576 FLJ31818 7q31.1 hypothetical protein FLJ31818 LOC392635 7 hypothetical gene supported by BT009862; NM_003142 GTF2IRD1 7q11.23 GTF2I repeat domain containing 1 LOC392724 7 LOC392724 WBSCR23 7q11.23 Williams-Beuren syndrome chromosome region 23 SCIN 7p21.3 scinderin FLJ11273 7p21.3 hypothetical protein FLJ11273 DMTF1 7q21.1 cyclin D binding myb-like transcription factor 1 C7orf23 7q21.1-q21.2 chromosome 7 open reading frame 23 ARL4 7p21-p15.3 ADP-ribosylation factor-like 4 GTF2I 7q11.23 general transcription factor II, i FLJ14712 7p21.3 hypothetical protein FLJ14712 GPR85 7q31 G protein-coupled receptor 85 LOC392778 7 hypothetical gene supported by BX537645 TP53AP1 7q21.1 TP53 activated protein 1 CROT 7q21.1 carnitine O-octanoyltransferase GTF2IRD2 7q11.23 transcription factor GTF2IRD2 LOC389465 7 hypothetical gene supported by BT009862; NM_003142 ABCB4 7q21.1 ATP-binding cassette, sub-family B (MDR/TAP), member 4 LOC392725 7 similar to Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3) PMS2L5 7q11-q22 postmeiotic segregation increased 2-like 5 ABCB1 7q21.1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 SCIN 7p21.3 scinderin LOC392726 7 LOC392726 ARL4 7p21-p15.3 ADP-ribosylation factor-like 4 RPIB9 7q21.13 Rap2-binding protein 9 MCFP 7q21.13 mitochondrial carrier family protein ASK 7q21.3 mitochondrial carrier family protein ADAM22 7q21.1 a disintegrin and metalloproteinase domain 22
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
14 - 2586 - 468 - -
16 - 3261 - 715 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinepancreas    
Skin/Tegumentskin    
Urinarykidneytubulecollecting duct  
cells
SystemCellPubmedSpeciesStageRna symbol
Digestiveenterocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a gelsolin homology domain
  • three actin-binding sites
  • two phosphatidylinositol bisphosphate-binding sites
  • HOMOLOGY
    interspecies homolog to rattus LOC298975
    Homologene
    FAMILY
  • villin/gelsolin family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton
    basic FUNCTION
  • may have a regulatory function in exocytosis, affecting the organisation of the microfilament network
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS exocytosis transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • actin binding
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS