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FLASH GENE
Symbol SCIMP contributors: mct - updated : 29-05-2013
HGNC name SLP adaptor and CSK interacting membrane protein
HGNC id 33504
Location 17p13.2      Physical location : -
Synonym name
  • hypothetical protein LOC388325
  • chromosome 17 open reading frame 87
  • Csk-interacting membrane protein
  • Synonym symbol(s) DTFT5783, UNQ5783, FLJ32580, MGC163426, MGC163428, C17orf87
    DNA
    TYPE functioning gene
    STRUCTURE 24.18 kb     5 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 666 16.6 145 - 2011 21930792
    - - 2403 - 138 - 2011 21930792
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneB cell Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • palmitoylated transmembrane adaptor protein
  • involved in signal transduction after MHC-II stimulation and therefore serves as a regulator of antigen presentation and other antigen-presenting cell functions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binds to the BLNK adaptor protein and also to the inhibitory kinase CSK
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS