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FLASH GENE
Symbol SCGB2A2 contributors: - updated : 21-01-2004
HGNC name secretoglobin, family 2A, member 2
HGNC id 7050
Location 11q13      Physical location : 62.037.629 - 62.040.627
Genatlas name lacryglobin
Synonym name
  • lipophilin C ,breast cancer associated glycoprotein
  • mammaglobin 1
  • Synonym symbol(s) LIPHC,UGB2,MGB1
    DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Binding site   transcription factor
    text structure
  • two imperfect elements similar to estrogen and androgen-response elements
  • promoter with a polyoma enhancer related motif
  • Sp family sites,an Ap-1 consensus site and a binding site similar to the binding site of pregnancy-specific mammary factor
  • MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Reproductivefemale systembreast  lowly
     female systembreast   
    Respiratoryrespiratory tracttrachea   
    Urinarykidney    
    Visualeyelacrimal gland   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandular  
    cell lineage
    cell lines breast carcinoma cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophilic
    STRUCTURE
    motifs/domains
    19AA hydrophobic peptide signal sequence
    conjugated GlycoP
    HOMOLOGY
    interspecies homolog to rattus prostatein
    intraspecies homolog to UGB,MGB2
    Homologene
    FAMILY
  • uteroglobin family
  • lipophilin subfamily
  • CATEGORY protooncogene , signaling
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION may be having androgen binding activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein SCGB1D2(mammaglobin/lipophilin B complex )
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS