Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | SCA8 | contributors: mct/npt - updated : 05/11/2008 |
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Corresponding disease |
| ||
Location | 13q21 Physical location : - | ||
Genatlas name | spinocerebellar ataxia 8 | ||
Synonym name | see ATXN8OS |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | overlapping, gene in gene, opposite orientation, antisens |
text | antisense transcript to KLHL1 producing no protein |
STRUCTURE | 32.00 kb 5 Exon(s) |
motif | repetitive sequence triplet |
text structure | a non coding CTG repeat preceded by a polymorphic but stable CTA tract (1-21) |
MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | transcripts containing the SCA8 CUG repeat tract are alternatively spliced and polyadenylated (Nemes, 2000) |
EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||
organ(s) |
|
tissue |
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cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | unknown/unspecified |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm |
basic FUNCTION |
CELLULAR PROCESS | cell life, differentiation |
cell life, proliferation/growth | |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA | binding |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | SCA8 |
Susceptibility |
Variant & Polymorphism repeat | CTG trinucleotide repeat expansion |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |