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FLASH GENE
Symbol SASH3 contributors: mct - updated : 18-09-2017
HGNC name SAM and SH3 domain containing 3
HGNC id 15975
Location Xq26.1      Physical location : 128.913.891 - 128.929.174
Synonym name
  • chromosome X open reading frame 9
  • SH3 protein expressed in lymphocytes homolog
  • Synonym symbol(s) SLY, 753P9, CXorf9, SH3D6C, HACS2, 753P9
    DNA
    TYPE functioning gene
    STRUCTURE 15.29 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2707 41.5 380 - 2001 11470164
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Lymphoid    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • sterile alpha motif, Src homology 3
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adaptor , signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • playing a role in immune pathology
  • SASH3 binds to the promoter of sex chromosome-encoded and autosomal genes highly expressed postmeiotically and involved in chromatin regulation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TBL1XR1, interact with SASH3 in postmeiotic male germ cells
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS