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FLASH GENE
Symbol SAA2 contributors: - updated : 13-05-2004
HGNC name serum amyloid A2
HGNC id 10514
Location 11p15.1-p14.3      Physical location : 18.260.589 - 18.270.182
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 4.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
regulatory sequence Promoter
Binding site   HRE
text structure disrupted glucocorticoid response element (GRE) ,inactive in the promoter
MAPPING cloned Y linked Y status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Lymphoid/Immunethymus    
cells
SystemCellPubmedSpeciesStageRna symbol
 fibroblast
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY SAA family
CATEGORY secretory
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
basic FUNCTION acute phase reactant involved in acute-phase response, inflammatory response
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
induced by cytokine stimulation.
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS