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FLASH GENE
Symbol RXRG contributors: - updated : 28-12-2005
HGNC name retinoid X receptor, gamma
HGNC id 10479
Location 1q22-q23      Physical location : 165.370.158 - 165.414.592
Synonym symbol(s) NR2B3, RXRC
DNA
TYPE functioning gene
STRUCTURE 44.00 kb     10 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
HSD17B7 17p11.2 hydroxysteroid (17-beta) dehydrogenase 7 MGC48998 1q23.2 hypothetical protein MGC48998 RGS4 1q23.2 regulator of G-protein signalling 4 RGS5 1q23 regulator of G-protein signalling 5 CDCA1 1q23.1 cell division cycle associated 1 LOC388711 1 hypothetical gene supported by BC037210; NM_005342 PBX1 1q23 pre-B-cell leukemia transcription factor 1 LMX1A 1q22-q23 LIM homeobox transcription factor 1, alpha RXRG 1q22-q23 retinoid X receptor, gamma LOC284684 1q23.2 similar to cDNA sequence BC004853 LOC391125 1 similar to ribosomal protein S2; 40S ribosomal protein S2 MGST3 1q23 microsomal glutathione S-transferase 3 ALDH9A1 1q22-q23 aldehyde dehydrogenase 9 family, member A1 LOC54499 1q22-q25 putative membrane protein LOC391126 1 similar to 60S ribosomal protein L26 UMPK 1p34.1-p33 uridine monophosphate kinase LOC391127 1 similar to ribosomal protein S3a; 40S ribosomal protein S3a; v-fos transformation effector protein 1 LOC149297 1q23.3 similar to RIKEN cDNA C030014K22 gene LOC284685 1q23.3 similar to Ewing sarcoma breakpoint region 1 isoform EWS LOC391128 1 similar to hypothetical protein 4831428F09 LOC116123 1q23.3 hypothetical protein BC014341 LOC391129 1 similar to ribosomal protein L4; 60S ribosomal protein L4; homologue of Xenopus ribosomal protein L1 POGK 1q23.2 pogo transposable element with KRAB domain STAF42 1q23.3 SPT3-associated factor 42 LOC388712 1 similar to dJ782G3.1 (LISCH7 (liver-specific BHLH-ZIP transcription factor)) FLJ14904 1q23.3 hypothetical protein FLJ14904 GPA33 1q23.2 glycoprotein A33 (transmembrane) LOC92235 1q22-q24 hypothetical cardiac/skeletal muscle-expressed ORF LOC391130 1 similar to ribosomal protein S17 POU2F1 1q22-q23 POU domain, class 2, transcription factor 1 CD3Z 1q22-q23 CD3Z antigen, zeta polypeptide (TiT3 complex) SRD5BP1 1q23-q25 steroid-5-beta-reductase, beta polypeptide pseudogene 1 CREG 1q24 cellular repressor of E1A-stimulated genes MGC21854 1q22-q24 hypothetical protein MGC21854 MPZL1 1q23.2 myelin protein zero-like 1 FLJ21047 1q23.3 hypothetical protein FLJ21047 SAC DKFZP564B167 1q24 DKFZP564B167 protein PC326 1q23.3 PC326 protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Nervousbrain   moderately
Reproductivefemale systembreastmammary gland highly
Respiratorylung    
Visualeye   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal modulator domain
  • a central bipartite (class II) zinc finger DNA binding domain
  • a nuclear receptor dna-binding domain
  • a C terminal steroid-binding domain
  • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies ortholog to murine Rxrg
    homolog to Xenopus Xl.878
    homolog to C.elegans H01A20.1
    Homologene
    FAMILY
  • steroid/thyroid/retinoic receptor superfamily
  • nuclear hormone receptor family
  • NR2 subfamily
  • CATEGORY transcription factor , receptor nuclear
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION involved in retinoic acid response pathway
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein binding to retinoic acid X receptor
    cell & other
    REGULATION
    activated by 9-cis-retinoic acid,only (9-cis-RA)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS