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FLASH GENE
Symbol RUFY2 contributors: npt - updated : 18-11-2009
HGNC name RUN and FYVE domain containing 2
HGNC id 19761
Location 10q21.3      Physical location : 70.103.276 - 70.167.051
Synonym name
  • Rab4-interacting protein related
  • antigen MU-RMS-40.17
  • Synonym symbol(s) KIAA1537, RABIP4R, FLJ10063, ZFYVE13
    DNA
    TYPE functioning gene
    STRUCTURE 63.67 kb     18 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2696 - 403 - -
    - - 4520 - 641 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a N terminal RUN domain
  • a C terminal FYVE domain
  • two coiled-coid domain in-between
  • HOMOLOGY
    interspecies homolog to Drosophila CG4043
    homolog to murine Rabip4
    Homologene
    FAMILY
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endosome
    text colocalizing with early endosome antigen marker (EEA1),RAB4
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text endosomal traffick
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS