Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol RRNAD1 contributors: mct - updated : 09-06-2020
HGNC name ribosomal RNA adenine dimethylase domain containing 1
HGNC id 24273
Location 1q23.1      Physical location : -
Synonym name
  • CGI-41 protein
  • chromosome 1 open reading frame 66
  • Synonym symbol(s) CGI-41, C1orf66, METTL25B
    DNA
    TYPE functioning gene
    STRUCTURE 8.49 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2271 - 475 - 2013 24097068
    7 - 1786 - 277 - 2013 24097068
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
     intestinesmall intestine  highly
    Reproductivefemale systemuteruscervix highly
    Visualeye   predominantly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine Bc023814
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
  • involved in ribosome processing, protein synthesis, cell cycle and cell proliferation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic
    signaling
    rRNA modification
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PEAR1 cell-specific methylation sensitive region in endothelial cells and megakaryocytes that showed strong chromosomal interactions with RRNAD1, HDGF and PRCC
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS