Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | RRAD | contributors: mct - updated : 23-12-2011 |
HGNC name | Ras-related associated with diabetes |
HGNC id | 10446 |
|
Location | 16q22.1 Physical location : 66.955.581 - 66.959.439 |
Synonym name | RAS (RAD and GEM) like GTP binding 3 |
Synonym symbol(s) | RAD, RAD1, REM3 |
DNA |
TYPE | functioning gene |
STRUCTURE | 3.86 kb 5 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
Binding site | |
text structure |
MAPPING | cloned | Y | linked | Y | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
intraspecies | homolog to GEM, highly |
Homologene |
FAMILY | |
k1 Ras oncogene superfamily member | |
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CATEGORY | protooncogene |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | its repression leads to QT prolongation and causes ventricular arrhythmias via modulation of CACNB2 in the heart |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility | to congestive heart failure |
Variant & Polymorphism other | RRAD Q66P contributes to cardiomyopathy and congestive heart failure |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |