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FLASH GENE
Symbol RPS29 contributors: mct - updated : 09-01-2023
HGNC name ribosomal protein S29
HGNC id 10419
Corresponding disease
DBA13 Diamond-Blackfan anemia 13
Location 14q21.3      Physical location : 50.044.052 - 50.053.094
Synonym name
  • small ribosomal subunit protein uS14
  • Synonym symbol(s) RS29, DBA13, S29, uS14
    DNA
    TYPE functioning gene
    STRUCTURE 9.04 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 510 - 53 - 2015 25901680
    3 - 735 - 67 - 2015 25901680
    3 - 302 - 56 - 2015 25901680
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialbarrier/lining   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumentkeratinocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • C2-C2 zinc finger-like domain
  • HOMOLOGY
    interspecies homolog to murine Rps29
    homolog to C.elegans B0412.4
    Homologene
    FAMILY
  • ribosomal protein S14P family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    intracellular,nucleus,nucleoplasm
    basic FUNCTION
  • 40S ribosomal protein S29
  • can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1)
  • CELLULAR PROCESS protein, translation/synthesis
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small 40S ribosomal subunit
  • INTERACTION
    DNA
    RNA binding to 4 RNA species
    small molecule metal binding,
  • Zn2+
  • protein
  • approximately 80 structurally distinct proteins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DBA13
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS