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FLASH GENE
Symbol RPS15 contributors: npt/mct - updated : 07-10-2009
HGNC name ribosomal protein S15
HGNC id 10388
Location 19p13.3      Physical location : 1.438.362 - 1.440.492
Synonym name
  • 40S ribosomal protein S15
  • homolog of rat insulinoma
  • insulinoma protein
  • Synonym symbol(s) RIG, MGC111130
    DNA
    TYPE functioning gene
    STRUCTURE 2.13 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Physical map
    ELA2 19p13.3 elastase 2, neutrophil DF 19p13.3 D component of complement (adipsin) TRAP95 MGC16353 19p13.3 hypothetical protein MGC16353 GPR54 19p13.3 G protein-coupled receptor 54 DRIL1 19p13.3 dead ringer-like 1 (Drosophila) WDR18 19p13.3 WD repeat domain 18 GRIN3B 19p13.3 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B C19orf6 19p13.3 chromosome 19 open reading frame 6 CNN2 21q11 calponin 2 ABCA7 19p13.3 ATP-binding cassette, sub-family A (ABC1), member 7 HA-1 19p13.3 ATP-binding cassette, sub-family A (ABC1), member 7 POLR2E 19p13.3 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa GPX4 19p13.3 glutathione peroxidase 4 (phospholipid hydroperoxidase) KIAA0963 19p13.3 Homo sapiens KIAA0963 protein (KIAA0963), mRNA. STK11 19p13.3 serine/threonine kinase 11 (Peutz-Jeghers syndrome) MGC40084 19p13.3 hypothetical protein MGC40084 ATP5D 19p13.3 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit MIDN 19pter-p13.3 midnolin MGC39338 19p13.3 hypothetical protein MGC39338 CIRBP 19p13.3-p13.2 cold inducible RNA binding protein FLJ20640 19p13.3 hypothetical protein FLJ20640 EFNA2 19p13.3 ephrin-A2 LOC388488 19 similar to Dip1-associated protein C MUM-1 NDUFS7 19p13 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) GAMT 19p13.3 guanidinoacetate N-methyltransferase DAZAP1 19p13.3 DAZ associated protein 1 RPS15 19p13.3 ribosomal protein S15 APCL 19p13.3 ribosomal protein S15 FLJ36666 19p13.3 hypothetical protein FLJ36666 PCSK4 19p proprotein convertase subtilisin/kexin type 4 DP1L1 19p13.3 polyposis locus protein 1-like 1 LOC339366 19p13.3 hypothetical protein LOC339366 LOC126520 19p13.3 hypothetical protein LOC126520 MBD3 19p13.3 methyl-CpG binding domain protein 3 UQCR 19p13.3 ubiquinol-cytochrome c reductase (6.4kD) subunit TCF3 19p13.3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) LOC126435 19p13.3 hypothetical LOC126435 LOC390874 19 similar to onecut 3 ATP8B3 19p13.3 ATPase, Class I, type 8B, member 3 EloA-BP1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 531 - 145 - Robledo (2008)
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text liver at the early stage of pregnancy
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to rattus rig (insulinoma gene)
    Homologene
    FAMILY
  • ribosomal protein S19P family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • 40S ribosomal protein S15
  • determinant of preribosomal nuclear export in human cells (Rouquette 2005)
  • having an essential role for proliferation in all cells (Robledo 2008)
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small 40S ribosomal subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • RPL37, RPS15 and RPS20 regulate the MDM2-TP53-MDM4 network
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS