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FLASH GENE
Symbol RPS12 contributors: KTN - updated : 28/11/2008
HGNC name ribosomal protein S12
HGNC id 10385
Location 6q23.2      Physical location : 133.135.707 - 133.138.702
Synonym name
  • 40S ribosomal protein S12
  • DNA
    TYPE functioning gene
    STRUCTURE 3.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 532 14.4 132 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver   moderately
    Lymphoid/Immunetonsils   highly
    Reproductivemale systemprostate  moderately
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text predominantly in umbilical cord
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated Other
    mono polymer heteromer , complex
    HOMOLOGY
    interspecies homolog to dog RPS12 (100 pc)
    homolog to chimpanzee RPS12 (97.7 pc)
    homolog to cow RPS12 (100 pc)
    homolog to murine Rps12 (100 pc)
    Homologene
    FAMILY
  • ribosomal protein S12e family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • involved in translation elongation
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the 40S ribosomal subunit
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other acetylated
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in colorectal cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS