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FLASH GENE
Symbol RPS10 contributors: npt/mct - updated : 19-11-2009
HGNC name ribosomal protein S10
HGNC id 10383
Corresponding disease
DBA9 Diamond-Blackfan anemia 9
Location 6p21.31      Physical location : 34.385.232 - 34.393.876
Synonym name 40S ribosomal protein S10
Synonym symbol(s) MGC88819
DNA
TYPE functioning gene
STRUCTURE 8.65 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
LYPLA2P1 6p21.31 lysophospholipase II pseudogene 1 KIFC1 6p21.3 kinesin family member C1 PHF1 6p21.3 PHD finger protein 1 C6orf82 6pter-p21.31 chromosome 6 open reading frame 82 MGC23166 BAK1 6p21.3 BCL2-antagonist/killer 1 ITPR3 6p21 inositol 1,4,5-triphosphate receptor, type 3 C6orf125 6p21.31 chromosome 6 open reading frame 125 IHPK3 6p2131-p21.2 inositol hexaphosphate kinase 3 LEMD2 6p21.31 LEM domain containing 2 MLN 6p21.3 motilin GRM4 6p21.3 glutamate receptor, metabotropic 4 LOC389381 6 LOC389381 LOC391914 6 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) CYCSL1 6p21.31 cytochrome c, somatic-like 1 HMGA1 6p21.3 high mobility group AT-hook 1 MGC57858 6p21.31 hypothetical protein MGC57858 LOC391915 6 hypothetical gene supported by U12465; NM_007209 NUDT3 6p21.2 nudix (nucleoside diphosphate linked moiety X)-type motif 3 RPS10 6p21.3 ribosomal protein S10 PACSIN1 6p21.3 protein kinase C and casein kinase substrate in neurons 1 SPDEF 6p21.3 SAM pointed domain containing ets transcription factor C6orf106 6p21.31 chromosome 6 open reading frame 106 MGC4614 6p21.31 hypothetical protein MGC4614 LOC391916 6 hypothetical gene supported by BC001032; NM_001014 SNRPC 6p21.2 small nuclear ribonucleoprotein polypeptide C C6orf107 6p21 chromosome 6 open reading frame 107 TAF11 6p21 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa ANKS1 6p21.31 ankyrin repeat and SAM domain containing 1 TCP11 6p21.2 t-complex 11 (mouse) CEGF3 6p21.3 CUB domain and EGF-like repeat containing 3 ZNF76 6p21.2 zinc finger protein 76 (expressed in testis) DEF6 6p21.33-p21.1 differentially expressed in FDCP 6 homolog (mouse) PPARD 6p21.2-p21.1 peroxisome proliferative activated receptor, delta
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 636 - 165 - Doherty (2010)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal plectin/S10 domain
  • HOMOLOGY
    Homologene
    FAMILY
  • ribosomal protein S10e family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 40S ribosomal protein S10
  • contribute to pre-rRNA processing (Doherty 2010)
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of the small 40S ribosomal subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DBA9
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS