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FLASH GENE
Symbol RPP30 contributors: - updated : 14-10-2004
HGNC name ribonuclease P/MRP 30kDa subunit
HGNC id 17688
Location 10q23.31      Physical location : 92.631.708 - 92.668.312
Synonym symbol(s) TSG15
DNA
TYPE functioning gene
STRUCTURE 30.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer complex
HOMOLOGY
interspecies homolog to murine Rnasep2
homolog to rattus LOC309518
Homologene
FAMILY eukaryotic/archaeal RNase P protein component 3 family
CATEGORY antigen
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleolus
basic FUNCTION
  • target for antisera from systemic sclerosis patients
  • endonucleolytic cleavage of RNA, removing 5'-extranucleotide from tRNA precursor
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of RNase P
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS