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FLASH GENE
Symbol RPL7A contributors: - updated : 26-02-2004
HGNC name ribosomal protein L7a
HGNC id 10364
Location 9q34.2      Physical location : 136.215.068 - 136.218.280
Synonym name
  • host gene for intronic RNU36A,B,C small nucleolar RNAs
  • surfeit 3
  • thyroid hormone receptor uncoupling protein
  • Synonym symbol(s) SURF3,TRUP
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster, opposite orientation
    text
  • see SURF@
  • RNU24 ,RNU36A,RNU36B,RNU36C embedded in introns 2,4,5 and 6 in opposite orientation and RNU24 (co-transcription)
  • STRUCTURE 3.00 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked Y status confirmed
    Physical map
    BARHL1 9q34 BarH-like 1 (Drosophila) DDX31 9q34.3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 GTF3C4 9q34.3 general transcription factor IIIC, polypeptide 4, 90kDa FLJ32704 9q34.3 hypothetical protein FLJ32704 C9orf9 9q34 chromosome 9 open reading frame 9 TSC1 9q34.1-q34.2 tuberous sclerosis 1 GFI1B 9q34.13 growth factor independent 1B (potential regulator of CDKN1A, translocated in CML) LOC158078 9q34 eukaryotic translation elongation factor 1 alpha 1 pseudogene LOC389801 9 LOC389801 GTF3C5 9q34 general transcription factor IIIC, polypeptide 5, 63kDa CEL 9q34.2 carboxyl ester lipase (bile salt-stimulated lipase) CELP 9q34.2-q34.3 carboxyl ester lipase pseudogene RALGDS 9q34.1-q34.2 ral guanine nucleotide dissociation stimulator FS 9q34 ral guanine nucleotide dissociation stimulator OBP2B 9q34 ral guanine nucleotide dissociation stimulator LOC286310 9q34.3 similar to Von Ebners gland protein precursor (VEG protein) (Tear prealbumin) (TP) (Tear lipocalin) (Lipocalin 1) ABO 9q34.1-q34.2 ABO blood group (transferase A, aplha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3galactosyltransferase) LOC392396 9 similar to Von Ebners gland protein precursor (VEG protein) (Tear prealbumin) (TP) (Tear lipocalin) (Lipocalin 1) SURF6 9q34.2 surfeit 6 SURF5 9q34.2 surfeit 5 RPL7A 9q34.2 ribosomal protein L7a SURF1 9q34.2 surfeit 1 SURF2 9q34.2 surfeit 2 SURF4 9q34.2 surfeit 4 ADAMTS13 9q34 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 C9orf7 9q34 chromosome 9 open reading frame 7 SLC2A6 9q34 solute carrier family 2 (facilitated glucose transporter), member 6 DBH 9q34.2 dopamine beta-hydroxylase (dopamine beta-monooxygenase) SARDH 9q33-q34 sarcosine dehydrogenase VAV2 9q34.2 vav 2 oncogene
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies ortholog to murine Rpl7a
    homolog to Drosophila RpL7A
    homolog to C.elegans Y24D9A.4a
    Homologene
    FAMILY L7AE family of ribosomal proteins
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION inhibiting the ability of a subclass of nuclear hormone receptors including thyroid hormone receptor to transactivate by preventing their binding to their DNA response elements
    CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component ribosomal protein being a component of the 60S subunit
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein binding to a subclass of nuclearhormone receptors including thyroid hormone receptor
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS