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FLASH GENE
Symbol RPL35A contributors: mct/npt - updated : 03-07-2009
HGNC name ribosomal protein L35a
HGNC id 10345
Corresponding disease
DBA5 Diamond-Blackfan anemia 5
Location 3q29      Physical location : 197.677.051 - 197.682.719
Synonym name cell growth-inhibiting gene 33 protein
DNA
TYPE functioning gene
STRUCTURE 5.67 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC389190 3 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) MFI2 3q28-q29 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 LOC391609 3 similar to immediate early protein homolog DLG1 3q29 discs, large (Drosophila) homolog 1 LOC391610 3 LOC391610 BDH 3q29 3-hydroxybutyrate dehydrogenase (heart, mitochondrial) LOC220729 3q29 similar to succinate dehydrogenase flavoprotein subunit LOC389191 3 hypothetical gene supported by BC053580 KIAA0226 3q29 KIAA0226 gene product DKFZp761B1514 3q29 hypothetical protein DKFZp761B1514 MGC4126 3q29 hypothetical protein MGC4126 DKFZp434B227 3q29 hypothetical protein DKFZp434B227 RPL35A 3q29-qter ribosomal protein L35a LMLN 3q29 leishmanolysin-like (metallopeptidase M8 family) LOC348840 3q29 hypothetical protein LOC348840 LOC389192 3 similar to FSHD Region Gene 2 protein LOC389193 3 hypothetical gene supported by BC014971; NM_020040 LOC389194 3 LOC389194 LOC339493 3q29 similar to bA476I15.3 (novel protein similar to septin)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 511 12.41 110 - Robledo (2008)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • ribosomal protein L35Ae family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 60S ribosomal protein L35A
  • having an essential role for proliferation in all cells (Robledo 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DBA5
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in glioblastoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS