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FLASH GENE
Symbol RPL30 contributors: mct - updated : 07-02-2011
HGNC name ribosomal protein L30
HGNC id 10333
Location 8q22.2      Physical location : 99.053.942 - 99.057.773
DNA
TYPE functioning gene
STRUCTURE 3.83 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC392254 8 similar to glyceraldehyde-3-phosphate dehydrogenase LOC392255 8 similar to growth and differentiation factor 6 UQCRB 8q22 ubiquinol-cytochrome c reductase binding protein CGI-12 8q22.1 CGI-12 protein PTDSS1 8q22 phosphatidylserine synthase 1 SDC2 8q22-q23 syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) PGCP 8q22.2 plasma glutamate carboxypeptidase KIAA1750 8q22.1 KIAA1750 protein LOC286150 8q22.1 similar to 40S ribosomal protein S2 LYRIC 8q22.1 LYRIC/3D3 LAPTM4B 8q22.1 lysosomal associated protein transmembrane 4 beta LOC389678 8 similar to hypothetical protein LOC51249 RPS23P1 8q23 ribosomal protein S23 pseudogene 1 MATN2 8q22 matrilin 2 RPL30 8q22-q24 ribosomal protein L30 FLJ39553 8q22.2 hypothetical protein FLJ39553 UK114 8q22 hypothetical protein FLJ39553 POP1 8q22.1 processing of precursors 1 FLJ13955 8q22.2 hypothetical protein FLJ13955 KCNS2 8q23.3-q24.11 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 STK3 8q22.2 serine/threonine kinase 3 (STE20 homolog, yeast) MRP63P7 8q22.2 mitochondrial ribosomal protein 63 pseudogene 7 OSR2 8q22.2 odd-skipped-related 2A protein COH1 8q22.2 Cohen syndrome 1 COX6C 8q22-q23 cytochrome c oxidase subunit VIc DKFZP434I092 8q22.3 DKFZP434I092 protein LOC286151 8q22.3 similar to RIKEN cDNA 4930533G20 POLR2K 8q22 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa SPAG1 8q22 sperm associated antigen 1 RNF19 8q22 ring finger protein 19 LOC157567 8q22.3 hypothetical protein LOC157567
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 524 - 115 - -
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines Hela cell
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to D8S1364E,likely
Homologene
FAMILY
  • ribosomal protein L30e family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 60S ribosomal protein L30
  • play an important role in p53 activation in response to nucleolar stress
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • constituent of ribosome, large subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in medulloblastoma is adversely associated with with adverse outcome
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS