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FLASH GENE
Symbol RPL3 contributors: - updated : 24-06-2004
HGNC name ribosomal protein L3
HGNC id 10332
Location 22q13.1      Physical location : 39.708.887 - 39.715.670
Synonym symbol(s) MGC104284
DNA
TYPE functioning gene
SPECIAL FEATURE
text
  • including RNU43, RNU86A, RNU83A, RNU83B respectively in introns 1, 3, 5, 7
  • conserved faetures of C/D class of snoRNAS in introns 1 (043), 3(U82), 5(U83a), 7(U83b)
  • STRUCTURE 6.00 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    Physical map
    APOBEC3A 22q13.1-q13.2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A APOBEC3B 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B APOBEC3C 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C APOBEC3D 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D APOBEC3E 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene APOBEC3F 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F APOBEC3G 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G ARP10 22q13.1 ARP10 protein COX5BL7 22pter-p13 cytochrome c oxidase subunit Vb-like 7 CBX7 22q13.1 chromobox homolog 7 LOC391332 22 similar to hepatitis C virus core-binding protein 6; cervical cancer oncogene 3 FLJ23865 22q13.1 hypothetical protein FLJ23865 PDGFB 22q13.1 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) RPL3 22q13.1 ribosomal protein L3 SYNGR1 22q13.1 synaptogyrin 1 MAP3K7IP1 22q13.1 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 LOC388902 22 LOC388902 MGAT3 22q13.1 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase FLJ20232 22q13 hypothetical protein FLJ20232 ATF4 22q13.1 activating transcription factor 4 (tax-responsive enhancer element B67) MGC52010 22q13.2 hypothetical protein MGC52010 CACNA1I 22q13.1 calcium channel, voltage-dependent, alpha 1I subunit
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY L3P family of ribosomal proteins,multiple sno RNA host gene family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 60S ribosomal protein L3 contributing to tat-mediated transactivation
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component ribosome,60S subunit
    INTERACTION
    DNA
    RNA binding to rRNA
    small molecule other,
    protein
    cell & other binding TAR,i.e,the LTR mediating the activation of viral HIV.1 gene expression by the TAL protein
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    related resource MITOP database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS