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Symbol RPL17 contributors: mct/npt - updated : 11-02-2010
HGNC name ribosomal protein L17
HGNC id 10307
Location 18q21.1      Physical location : 47.014.858 - 47.018.906
Synonym name
  • 60S ribosomal protein L23
  • gene encoding putative NFkB activating protein
  • Synonym symbol(s) rpL23, RL17, FLJ92089, MGC117162, PD-1
    DNA
    TYPE functioning gene
    STRUCTURE 4.05 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 942 - 184 - 2002 11875025
    7 - 693 - 184 - 2002 11875025
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    tissu     
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialbarrier/lining   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Skin/Tegumentkeratinocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer , complex
    HOMOLOGY
    interspecies homolog to C.elegans ra5.8
    Homologene
    FAMILY
  • ribosomal protein L22P family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • 60S ribosomal protein L17a
  • may have a signaling function such that it can recognize a TM segment inside the ribosome and triggers rearrangements of the translocon, priming it for subsequent TM segment integration
  • important inhibitory molecules frequently expressed by ovarian tumor-infiltrating lymphocytes
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • constituent of ribosome, large subunit
  • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS