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FLASH GENE
Symbol RPL12 contributors: mct - updated : 05-01-2013
HGNC name ribosomal protein L12
HGNC id 10302
Location 9q33.3      Physical location : 130.209.954 - 130.213.684
DNA
TYPE functioning gene
STRUCTURE 3.76 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
ZNF297B 9p24.1-q22.33 zinc finger protein 297B RALGPS1A 9q34.11-q34.12 zinc finger protein 297B ANGPTL2 9q34 angiopoietin-like 2 DKFZp761J1523 9q34.13 hypothetical protein DKFZp761J1523 SLC2A8 9q34.1-q34.2 solute carrier family 2, (facilitated glucose transporter) member 8 ZNF79 9q34.1 zinc finger protein 79 (pT7) RPL12 9q34 ribosomal protein L12 LRSAM1 9q34.13 leucine rich repeat and sterile alpha motif containing 1 DKFZP434H0820 9q34.13 hypothetical protein DKFZp434H0820 STXBP1 9q34.1 syntaxin binding protein 1 LOC286207 9q34.13 hypothetical protein LOC286207 LOC138428 9q34.13 hypothetical protein LOC138428 TTC16 9q34.13 tetratricopeptide repeat domain 16 TOR2A 9q34.11 torsin family 2, member A SH2D3C 9q34.13 SH2 domain containing 3C CDK9 9q34.1 cyclin-dependent kinase 9 (CDC2-related kinase) FPGS 9cen-q34.11 folylpolyglutamate synthase ENG 9q34.1 endoglin (Osler-Rendu-Weber syndrome 1) AK1 9q34.12 adenylate kinase 1 ST6GALNAC6 9q34.13 adenylate kinase 1 SIAT7D 9q34.1 sialyltransferase 7D ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) MGC46424 9q34.13 hypothetical protein MGC46424 LOC389790 9 similar to phosphatidylinositol phosphate kinase-like protein DPM2 9q34.13 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit FLJ10232 9q34.13 hypothetical protein FLJ10232
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 - 674 - 165 - 2002 11809816
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines Hela cell
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus Rpl12
Homologene
FAMILY
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic,ribosome
basic FUNCTION
  • accesses the importin 11 pathway as a major route into the nucleus
  • uses a distinct nuclear import pathway that may contribute to a mechanism for regulating ribosome synthesis and/or maturation
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component constituent of ribosome,large subunit
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • specifically and directly interacted with importin 11 (IPO11)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS