basic FUNCTION
| may play an important role in redox signaling in cancer cells |
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integral mitochondrial inner-membrane protein that coordinately regulates mitochondrial morphology and cell proliferation  |
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ROMO1-derived ROS play potentially an important role in apoptotic cell death triggered by withdrawal of cell survival factors  |
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recruits BCL2L1 to reduce the mitochondrial membrane potential, resulting in ROS production and apoptotic cell death  |
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molecular bridge between TNF-alpha signaling and the mitochondria for ROS production that triggers TNF-alpha-mediated apoptosis, as well as a novel target in the development of anti-inflammatory agents that block the origin of ROS production  |
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subsequently triggers SKP2-mediated ubiquitylation and degradation of MYC  |
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is responsible for a serum deprivation-induced increase in reactive oxygen species (ROS)  |
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involved in generation of reactive oxygen species in mitochondria  |
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localized in the mitochondria and mediates mitochondrial ROS production through complex III of the mitochondrial electron transport chain  |
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mediates mitochondrial ROS production and apoptosis induced by oxidative stress in lung epithelial cells  |
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is a new translocase constituent with an exceptionally short half-life  |