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FLASH GENE
Symbol RNPEP contributors: - updated : 29-06-2004
HGNC name arginyl aminopeptidase (aminopeptidase B)
HGNC id 10078
Location 1q32.1-q32.2      Physical location : 201.951.765 - 201.975.274
Synonym symbol(s) APB
EC.number 3.4.11.6
DNA
TYPE like-sequence
STRUCTURE 23.00 kb     11 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
Physical map
TMEM9 1q41 transmembrane protein 9 LOC388724 1 similar to hypothetical protein FLJ37794 DKFZp434B1231 1q32.1 eEF1A2 binding protein PKP1 1q32 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) TNNT2 1q32 troponin T2, cardiac LAD1 1q25.1-q32.3 ladinin 1 TNNI1 1q31.3 troponin I, skeletal, slow PHLDA3 1q31.3-q32.1 pleckstrin homology-like domain, family A, member 3 CSRP1 1q32.1 cysteine and glycine-rich protein 1 LOC388725 1 similar to mKIAA1151 protein NAV1 1q32.1 neuron navigator 1 IPO9 1q31.3 importin 9 LOC149345 LMOD1 1q32 leiomodin 1 (smooth muscle) TIMM17A 1q31.3-q32 translocase of inner mitochondrial membrane 17 homolog A (yeast) LOC391151 1 similar to 60S ribosomal protein L10 (QM protein homolog) RNPEP 1q32.1-q32.2 arginyl aminopeptidase (aminopeptidase B) ELF3 1q32.2 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) ET(B)R-LP-2 1q32.1 endothelin type b receptor-like protein 2 LOC127829 PTPN7 1q32.1 protein tyrosine phosphatase, non-receptor type 7 LOC388726 1 similar to osteotesticular protein tyrosine phosphatase LOC148713 1q32.1 similar to Osteotesticular phosphatase; protein tyrosine phosphatase, receptor type, V LGR6 1q32.1 leucine-rich repeat-containing G protein-coupled receptor 6 HSPC150 1q32.1 HSPC150 protein similar to ubiquitin-conjugating enzyme PPP1R12B 1q32.1 protein phosphatase 1, regulatory (inhibitor) subunit 12B HCP4 1q32.1 cytochrome c, somatic pseudogene SYT2 1q31.3 synaptotagmin II PLU-1 1q32.1 putative DNA/chromatin binding motif LOC388727 1 LOC388727 LOC163556 1q32.1 similar to RIKEN cDNA 4931440L10
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestine   
 stomach    
Endocrinepancreas    
Reproductivefemale systemovary   
Skin/Tegumentskin    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to leukotriene-A4 hydrolase,structurally
Homologene
FAMILY peptidase family M1
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • potential metallopeptidase,aminopeptidase B,zinc dependent
  • exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    zinc ion
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS