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FLASH GENE
Symbol RNGTT contributors: npt/ - updated : 11-02-2002
HGNC name RNA guanylyltransferase and 5'-phosphatase
HGNC id 10073
Location 6q16      Physical location : 89.319.988 - 89.673.348
Synonym name
  • mRNA-capping enzyme
  • polynucleotide 5'-triphosphatase
  • mRNA guanylyltransferase
  • Synonym symbol(s) HCE, HCE1, hCAP, DKFZp686J2031 , CAP1A
    EC.number 3.1.3.33, 2.7.7.50
    DNA
    TYPE functioning gene
    STRUCTURE 353.36 kb     16 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map cen - AFMb2982g9 - RNGTT - AFM185xd10 - AFM310xa9 - D6S275 - qter
    Authors Pillutla (98)
    Physical map
    CGA 6q12-q21 glycoprotein hormones, alpha polypeptide LOC391950 6 similar to Reticulocalbin 1 precursor LOC389415 6 LOC389415 ZNF292 6q15 zinc finger protein 292 GJB7 6q15 gap junction protein, beta 7 C6orf162 6q15-q16.1 chromosome 6 open reading frame 162 C6orf163 6q15 chromosome 6 open reading frame 163 C6orf165 6q15 chromosome 6 open reading frame 165 TAF13P 6q14.3-15 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, pseudogene SLC35A1 6q16.1 solute carrier family 35 (CMP-sialic acid transporter), member A1 RARSL 6q16.1 arginyl-tRNA synthetase-like ORC3L 6q14.3-16.3 origin recognition complex, subunit 3-like (yeast) C6orf166 6q15 chromosome 6 open reading frame 166 SPACA1 6q16.1 sperm acrosome associated 1 CNR1 6q14-q15 cannabinoid receptor 1 (brain) LOC391951 6 similar to ribosomal protein S14 ACTBP8 6q13 actin, beta pseudogene 8 RNGTT 6q16 RNA guanylyltransferase and 5'-phosphatase HCP16 6q15 cytochrome c, somatic pseudogene PNRC1 6q16.1 proline-rich nuclear receptor coactivator 1 SRrp35 6q16.1 serine-arginine repressor protein (35 kDa) ACY1L2 6q16.1 aminoacylase 1-like 2 GABRR1 6q13-q15.3 gamma-aminobutyric acid (GABA) receptor, rho 1 GABRR2 6q14-q16.3 gamma-aminobutyric acid (GABA) receptor, rho 2 UBE2J1 6q16.1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) RRAGD 6q15-q16 Ras-related GTP binding D ANKRD6 6q14.2-q16.1 ankyrin repeat domain 6 DJ122O8.2 6q14.2-q16.1 hypothetical protein dJ122O8.2 MDN1 6q15 MDN1, midasin homolog (yeast) CASP8AP2 6q16.1 CASP8 associated protein 2 CX62 6q15-q16 connexin 62 LOC285793 6q16.1 hypothetical LOC285793 BACH2 6q15 BTB and CNC homology 1, basic leucine zipper transcription factor 2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 - 4463 68.4 597 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • bifunctional enzyme containing a N terminal domain with RNA 5'-triphosphatase activity
  • a C terminal with guanylyl guanyllyltransferase activity
  • HOMOLOGY
    Homologene
    FAMILY
  • eukaryotic GTase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • messenger RNA capping bifunctional enzyme
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS