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FLASH GENE
Symbol RNF141 contributors: - updated : 24-02-2006
HGNC name ring finger protein 141
HGNC id 21159
Location 11p15.3      Physical location : 10.533.224 - 10.562.774
Synonym name
  • C3HC4-like zinc finger protein
  • zinc finger protein 26 homolog (mouse)
  • Synonym symbol(s) ZNF230, ZFP26, MGC8715
    DNA
    TYPE functioning gene
    STRUCTURE 26.00 kb     6 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    NRIP3 11p15.3 nuclear receptor interacting protein 3 SCUBE2 11p15.3 signal peptide, CUB domain, EGF-like 2 FLJ46111 11p15.3 FLJ46111 protein RAB6IP1 11p15.3 RAB6 interacting protein 1 KIAA0033 11p15.3 KIAA0033 protein IPO7 11p15.3 importin 7 ZNF143 11p15.4-p15.3 zinc finger protein 143 (clone pHZ-1) WEE1 11p15.3 WEE1 homolog (S. pombe) LOC387752 11 similar to 60S ribosomal protein L23a LOC387753 11 similar to 60S ribosomal protein L21 SWAP70 11p15 Homo sapiens SWAP-70 protein (SWAP70), mRNA. CMT4B2 11p15.3 Charcot-Marie-Tooth neuropathy 4B2 (autosomal recessive, with myelin outfolding) ADM 11p15.4 adrenomedullin LOC338749 11p15.3 hypothetical LOC338749 AMPD3 11p15 adenosine monophosphate deaminase (isoform E) RNF141 11p15.3 ring finger protein 141 XLKD1 11p15 extracellular link domain containing 1 MRVI1 11p15 murine retrovirus integration site 1 homolog SH2BP1 11pter-p15.4 SH2 domain binding protein 1 (tetratricopeptide repeat containing) EIF4G2 11p15 eukaryotic translation initiation factor 4 gamma, 2 LOC58486 11p15.3 transposon-derived Buster1 transposase-like protein MGC71806 11p15.3 similar to Hypothetical protein LOC233733 USP47 11p15.2 ubiquitin specific protease 47
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1100 26.5 230 - Zhang
    - - 4000 - - various tissues not in testis Zhang
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivemale systemtestis   
    Urinarykidney    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Reproductivespermatid
    Reproductivespermatocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a RING (C3HC4) zinc finger motif
    conjugated MetalloP
    HOMOLOGY
    interspecies ortholog to murine Rnf141
    ortholog to rattus rnf141
    Homologene
    FAMILY
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in the maintenance of normal human male fertility
  • CELLULAR PROCESS cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    text spermatogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS