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FLASH GENE

Symbol

RNF126

contributors: - updated : 03-08-2004

HGNC name	ring finger protein 126
HGNC id	21151

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19p13.3      Physical location : 647.529 - 663.233
Synonym symbol(s)	MGC1022, FLJ20552, MGC14317

DNA

TYPE	functioning gene
STRUCTURE	15.00 kb     9 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 1457 - 326 - Saurin variant 2 - - 1658 33.8 311 - Saurin an extra segment, causing a translation frameshift resulting in an isoform with a distinct and shorter C-terminus

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a RING finger

HOMOLOGY

interspecies	homolog to murine 2610010O19Rik
	homolog to rattus LOC314613

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

intracellular

basic FUNCTION

may have an ubiquitin protein ligase activity

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	metal binding,
	ion Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS