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FLASH GENE
Symbol RHPN1 contributors: - updated : 26-07-2004
HGNC name rhophilin, Rho GTPase binding protein 1
HGNC id 19973
Location 8q24.3      Physical location : 144.451.024 - 144.466.389
Synonym name
  • rhophilin 1
  • outer dense fiber of sperm tails 5
  • Synonym symbol(s) KIAA1929, RHPN, ODF5
    DNA
    TYPE functioning gene
    STRUCTURE 13.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    CYP11B2 8q24.3 cytochrome P450, family 11, subfamily B, polypeptide 2 LY6E 8q24.3 lymphocyte antigen 6 complex, locus E FLJ37131 8q24.3 hypothetical protein FLJ37131 HHCM 8q24.3 Mahlavu hepatocellular carcinoma LY6H 8q24.3 lymphocyte antigen 6 complex, locus H LOC338328 8q24.3 high density lipoprotein-binding protein FLJ38705 8q24.3 hypothetical protein FLJ38705 GLI4 8q24.3 GLI-Kruppel family member GLI4 FLJ14129 8q24.3 hypothetical protein FLJ14129 LOC389691 8 LOC389691 TOP1MT 8q24.3 LOC389691 MGC3113 8q24 hypothetical protein MGC3113 RHPN1 8q24.3 rhophilin, Rho GTPase binding protein 1 LOC389692 KIAA0150 8q24.3 rhophilin, Rho GTPase binding protein 1 LOC389693 8 LOC389693 FLJ12150 8q24.3 hypothetical protein FLJ12150 LOC389694 8 similar to FLJ46354 protein PP3856 8q24.3 similar to CG3714 gene product EEF1D 13q12 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) TIGD5 8q24.3 tigger transposable element derived 5 FLJ13852 8q24.3 hypothetical protein FLJ13852 TSTA3 8q24.3 tissue specific transplantation antigen P35B KIAA0628 8q24.3 tissue specific transplantation antigen P35B LOC286075 8q24.3 hypothetical protein LOC286075 LOC286076 8q24.3 similar to hypothetical protein ERK8  extracellular signal-regulated kinase 8 FLJ46072 8q24.3 FLJ46072 protein LOC389695 8 LOC389695 LOC389696 8 LOC389696 LOC286080 8q24.3 similar to CG3104-PA
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one BRO1 domain
  • one HR1 domain
  • one PDZ/DHR domain
  • HOMOLOGY
    interspecies homolog to rattus LOC30030
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • regulates actin cytoskeleton organization
  • may serve as a target for Rho
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein specifically binding GTP-Rho
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS