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FLASH GENE
Symbol RFPL4A contributors: mct - updated : 04-09-2008
HGNC name ret finger protein-like 4A
HGNC id 16449
Location 19q13.42      Physical location : 56.270.506 - 56.274.539
Synonym symbol(s) RFPL4, RNF210
DNA
TYPE functioning gene
STRUCTURE 4.16 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivegerm cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a RING finger-like domain
  • a B30.2 motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • encodes a putative E3 ubiquitin-protein ligase, mediates protein degradation pathways important for gametogenesis or early embryonic development
  • targets cyclin B1 for proteasomal degradation, a key aspect of oocyte cell cycle control during meiosis and the crucial oocyte-to-embryo transition to mitosis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS