basic FUNCTION
| deoxycytidyl (dCMP)-transferase, template DNA dependent, specifically inserting a dCMP residue |
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required for mutagenesis induced by UV light |
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opposite a DNA template G and opposite an apurinic site |
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involved in the tolerance of DNA damage by translesion DNA synthesis |
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playing an important role for maintaining genetic integrity through translesion DNA synthesis |
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involved in the tolerance of DNA damage by replicative bypass |
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REV1, REV3L and MAD2L2 play important roles in translesion DNA synthesis (TLS) in which DNA replication bypasses blocking lesions (pMID: 21926160) |
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translesion synthesis (TLS) DNA polymerase involved in bypass replication across sites of DNA damage and postreplicational gap-filling |
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REV1, REV3L, and MAD2L2 are pivotal proteins in translesion DNA synthesis, which allows DNA synthesis even in the presence of DNA damage |
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plays a pivotal role in mediating DNA damage-induced mutagenesis |
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is required for successful replication of G-quadruplex DNA (G4 DNA) |