basic FUNCTION
| reduction of all-trans-retinal most noticeably at higher light intensities and prolonged illumination |
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catalyzes reduction of all-trans-retinal in the rod outer segment, most noticeably at higher light intensities and prolonged illumination, but is not an essential enzyme of the retinoid cycle |
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RDH8 is necessary for reducing the bulk of the all-trans-retinal released by photoactivated rhodopsin in the outer segment |
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RDH12, RDH8, both enzymes are required to reduce all-trans-retinal generated after bleaching and present in both photoreceptor inner and outer segments |
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RDH8 activity is essential for reducing the majority of the retinal generated in the outer segment |
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is responsible for reducing the bulk of the all-trans-retinal released from photoactivated rhodopsin after light exposure, but some retinal leaks to the inner segment, even in the presence of RDH8 |