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FLASH GENE
Symbol RDH14 contributors: - updated : 24-03-2007
HGNC name retinol dehydrogenase 14 (all-trans and 9-cis)
HGNC id 19979
Location 2p24.2      Physical location : 18.735.990 - 18.741.959
Synonym name
  • PAN2 protein
  • pancreas protein 2
  • Synonym symbol(s) PAN2
    EC.number 1.1.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 5.00 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC391354 2 similar to Mothers against decapentaplegic homolog interacting protein (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP) LOC388925 2 hypothetical gene supported by BC018859; NM_002802 VSNL1 2p24.3 visinin-like 1 SMC6L1 2p24.3 SMC6 structural maintenance of chromosomes 6-like 1 (yeast) LOC388926 2 similar to RIKEN cDNA 5830483C08 gene FLJ40869 2p24.3 similar to RIKEN cDNA 5830483C08 gene LOC343930 2p24.3 similar to pMesogenin1 KCNS3 2p23-p22.2 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 RDH14 2p24.1 retinol dehydrogenase 14 (all-trans and 9-cis) NT5C1B 2p24.1 5'-nucleotidase, cytosolic IB LOC388927 2 LOC388927 OSR1 3p22-p21.3 oxidative-stress responsive 1 LOC130500 2p24.3 similar to Uncharacterized hematopoietic stem/progenitor cells protein MDS029 LOC130502 2p24.3 similar to CG14894-PA KIAA1336 2p24.3 KIAA1336 protein MATN3 2p24-p23 matrilin 3 LAPTM4A 2p24.3 lysosomal-associated protein transmembrane 4 alpha LOC391355 2 similar to 40S ribosomal protein S16 SDC1 2p24.1 syndecan 1
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver    
     stomach    
    Endocrineadrenal gland    
     pancreas    
     placenta    
     thyroid    
    Nervousbrain    
     spinal cord    
    Reproductivemale systemprostate   
    Respiratorylung    
     respiratory tracttrachea   
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneB cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a N-terminal hydrophobic domain
    HOMOLOGY
    interspecies homolog to murine Rdh14
    homolog to rattus LOC298881
    Homologene
    FAMILY short chain dehydrogenase/reductase (SDR) family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION functions as a reductase and may contribute to the reduction of retinaldehyde to retinol
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
    NADPH and NADP+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS