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FLASH GENE
Symbol RBP7 contributors: - updated : 10-02-2006
HGNC name retinol binding protein 7, cellular
HGNC id 30316
Location 1p36.22      Physical location : 10.057.254 - 10.076.077
Synonym name
  • retinoid binding protein 7
  • putative cellular retinol-binding protein CRBP IV
  • Synonym symbol(s) HGNC30316, CRBP4, CRBPIV, MGC70641, RP11-490H15.1
    DNA
    TYPE functioning gene
    STRUCTURE 18.00 kb     4 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveintestinelarge intestinecolon  
    Lymphoid/Immunelymph node    
    Urinarykidney   highly
    cell lineage
    cell lines lung carcinoma
    fluid/secretion
    at STAGE
    physiological period fetal
    Text heart, spleen
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
    secondary structure
  • a single eight-stranded continuously hydrogen-bonded antiparallel beta-barrel
  • HOMOLOGY
    interspecies homolog to murine Rbp7
    intraspecies paralog to RBP1, RBP2
    Homologene
    FAMILY distinct CRBP family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • involved in stability, internalization, intercellular transfer, homeostasis and metabolism of vitamin A
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism vitamin
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
    retinol binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS