basic FUNCTION
| delivery of retinol from the liver stores to peripheral tissues |
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adipocyte-derived 'signal' that may contribute to the pathogenesis of type 2 diabetes |
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adipokine, linking glucose uptake in adipocytes with systemic insulin sensitivity |
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secreted by adipocytes, and associated with insulin resistance |
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adipocytokine that may link obesity and insulin resistance |
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RBP4 secretion was restricted to mature adipocytes, further indicating that RBP4 is strongly related to differentiation of adipocytes |
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has a robust acute effect of enhancement of NO production via stimulation of part of the PI3K/Akt/eNOS pathway and inhibition of ERK1/2 phosphorylation which results in vasodilatation |
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RBP4 and its membrane receptor STRA6 coordinate cellular retinol uptake |
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retinol-dependent metabolic function of RBP4 that may have important implications for the treatment of obesity |