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FLASH GENE
Symbol RASGEF1C contributors: - updated : 21-04-2005
HGNC name RasGEF domain family, member 1C
HGNC id 27400
Location 5q35.3      Physical location : 179.527.795 - 179.636.130
DNA
TYPE functioning gene
STRUCTURE 38.00 kb     14 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainlimbic systemhippocampus  
 gangliasensory gangliadorsal root  
Reproductivefemale systembreastmammary gland  
 male systemtestis   
Visualeye    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N-terminal RAS-GEF domain
  • a SH3 domain
  • HOMOLOGY
    Homologene
    FAMILY RasGEF domain family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION promoting the exchange of RAS-bound GDP by GTP
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS