Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | RAPGEF4 | contributors: shn - updated : 12/05/2012 |
HGNC name | Rap guanine nucleotide exchange factor (GEF) 4 |
HGNC id | 16626 |
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Location | 2q31.1 Physical location : 173.600.524 - 173.917.618 |
Synonym name | |
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Synonym symbol(s) | cAMP-GEF2, EPAC2, CGEF2, Nbla00496, CAMP-GEFII |
DNA |
TYPE | functioning gene |
STRUCTURE | 317.09 kb 31 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
Map | cen - D2S2381 - D2S326 - RAPGEF4 - D2S2307 - D2S2188 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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text | three transcripts (PMID: 11707077) |
EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | ortholog to Rapgef4, Rattus norvegicus |
ortholog to Rapgef4, Mus musculus | |
ortholog to RAPGEF4, Pan troglodytes |
Homologene |
FAMILY |
CATEGORY | receptor membrane G |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm | |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | exocytosis transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | nucleotide, |
protein | |
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cell & other |
REGULATION |
activated by |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
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Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |