| basic FUNCTION
| multi-functional ATPase that couples the movement of substances with ATP-hydrolysis |
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involved in the transport of glutathione conjugating and xenobiotics potentially contributing to multidrug resistance |
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mediating vinorelbine transport and capable of conferring drug accumulation defect and resistance to lung cancer cells |
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plays a prominent anti-apoptotic role selectively in cancer cells |
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involved in certain cellular functions including membrane plasticity and movement (as a primary 'effector' in the Ral pathway, perhaps functioning as a GTPase activating protein, or GAP), and as a component of clathrin-coated pit-mediated receptor-ligand endocytosis-a process that mediates movement of membrane vesicles |
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multifunctional transporter protein that serves as an energy-dependent efflux mechanism for endogenously generated toxic metabolites as well as exogenous toxins, including chemotherapy drugs  |
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induced by oxidative stress, and could play a role in insulin resistance seen in pathological conditions characterized by increased oxidative stress |
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necessary for metastasis of cancer cell lines |
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RALA and RALBP1 regulate mitochondrial fission at mitosis |
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disruption of its ATPase function impaired invadopodium formation |
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is a modular protein capable of participating in many cellular functions |
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REPS1, and RALBP1 are present early during embryonic development, but they are active only at the end of gastrulation |
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required for angiogenesis and for efficient neovascularization of primary solid tumors |
