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FLASH GENE
Symbol RAET1L contributors: mct - updated : 01-12-2012
HGNC name retinoic acid early transcript 1L
HGNC id 16798
Location 6q25.1      Physical location : 150.341.266 - 150.346.668
Synonym symbol(s) ULBP6
DNA
TYPE functioning gene
STRUCTURE 5.40 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 802 27.4 246 - 2002 11827464
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines tumor cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • alpha 1 and alpha 2 domain
  • GPI domain
    • HOMOLOGY
    intraspecies homolog to UL16 binding protein 2
    Homologene
    FAMILY
  • MHC class I family
  • RAET1 family
    • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    text glycosylphosphatidylinositol (GPI)-anchored
    basic FUNCTION
  • critical role for KLRK1-RAET1L interactions in determining stem cell transplantation clinical outcome
  • RAET1L may have an important influence on regulating the strength of the alloreactive immune response
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • bound to CMV immune evasion molecule UL16
  • KLRK1-RAET1L interactions
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS