Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | RABEP1 | contributors: mct - updated : 05-03-2017 |
HGNC name | rabaptin, RAB GTPase binding effector protein 1 |
HGNC id | 17677 |
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Location | 17p13.2 Physical location : 5.185.557 - 5.289.131 |
Synonym name | |
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Synonym symbol(s) | RAB5EP, RABPT5, NY-REN-17 |
DNA |
TYPE | functioning gene |
STRUCTURE | 103.55 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
| N and C terminal region containing alpha helical and heptad repeat characteristic of coiled coil domain |
HOMOLOGY |
interspecies | ortholog to murine Rab5ep-pending |
Homologene |
FAMILY |
CATEGORY | transport carrier |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,endosome | |
intracellular,cytoplasm,cytosolic | |
text |
basic FUNCTION | |
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CELLULAR PROCESS | protein |
PHYSIOLOGICAL PROCESS | endocytosis transport , cellular trafficking transport |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
activated by | cleaved caspase 3 during apoptosis |
Other | recruited by RAB5 to early endosomes,in a GTP dependent manner |
ASSOCIATED DISORDERS |
ANIMAL & CELL MODELS |